Exemestane, which is the active compound and chemical name of Aromasin, works by blocking the effects of estrogen in the breast tissue so the growth of cancer can be limited or stopped.

Exemestane (Aromasin) Structure

 

This breast tissue targeted estrogen blocking action of this aromatase inhibitor is useful for bodybuilders who use anabolic steroids with aromatizing effects which cause estrogenic side effects – specifically gynecomastia (gyno), or male breast tissue enlargement.

 

When we let gyno take hold while using steroids, the effects are not only ugly and embarrassing to look at but they can be impossible to get rid of without surgery. So making use of an aromatase inhibitor like Aromasin is one of the most important things a male steroid user must do. It would also gain a fair amount of popularity in Post Cycle Therapy (PCT) plans among steroid users. It was not the first AI to gain such popularity but would prove to be a little more advantageous for this purpose than most AI’s.

 

Aromasin is officially classified as a steroidal suicide Aromatase Inhibitor, and carries the ability to inhibit the aromatase enzyme, which is responsible for the production or conversion of testosterone to estrogen. Aromasin has the ability to block aromatization, which in turn inhibits the production of estrogen, and thereby lowers the body’s serum estrogen levels. This will prove useful to the anabolic steroid user.

 

Many anabolic steroids have the ability to increase estrogen levels due to the aromatase process, specifically the conversion of testosterone to estrogen. This can lead to gynecomastia and water retention. Excess water retention can also promote high blood pressure when it becomes severe. Steroids that do not carry a strong estrogenic nature can also cause these effects, most notably gynecomastia if they carry a progestin nature. A prime example would be Nandrolone, which while it aromatizes only does so at 20% the rate of testosterone. However, it also carries a strong progestin nature, and progesterone has been well noted for carrying the ability to stimulate the estrogenic mechanism in the mammary tissue. By administering Aromasin during the use of anabolic steroids, this will inhibit the aromatase process, lower estrogen levels and protect the individual from estrogenic side effects. How effective is Aromasin? The product claims on average to have the ability to lower serum estrogen levels by 85%.

 

Aromasin also has the ability to stimulate natural testosterone production, which is precisely why some will include it during their PCT. Like Arimidex and Letrozole, Aromasin will stimulate the pituitary to release more Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), two hormones essential to natural testosterone production. While the other common AI’s share this trait, Aromasin has been shown to carry a slight androgenic effect, as well as the ability to increase the production of Insulin-Like Growth Factor-1 (IGF-1). This is a trait no other AI can claim to carry. By using Aromasin during PCT, the individual receives the desired testosterone boost necessary for recovery, but with the IGF-1 increase also creates a stronger anabolic atmosphere. This is deemed useful by some steroid users as it could potentially give them the ability to protect their lean tissue all the more during use. However, when we look at the direct effects of Aromasin as it pertains to PCT, we will find PCT use is normally not recommended despite these positive effects.

 

 

An important note: Aromasin will have no affect on dihydrotestosterone (DHT) derived anabolic steroids as they do not convert to estrogen. Such steroids cannot lead to gynecomastia or excess water retention; it is impossible. The exception would be Anadrol (Oxymetholone), while a DHT derivative, it carries with it a strong estrogenic nature. However, while estrogenic action is present, the hormone does not aromatize, meaning there is no aromatization for Aromasin to inhibit. The use of an AI will not affect the estrogenicity of Anadrol. For protection from such a steroid, the individual will need to inhibit activation of the estrogenic mechanism, and this will make SERM’s the first line of defense.

 

The final effects of Aromasin surround its use in a PCT plan. Due to the use of anabolic steroids natural testosterone production is suppressed. The rate of suppression will be dependent on the steroids being used, and to a degree, the total doses, but natural production will be suppressed nonetheless. Due to the need for a strong PCT and Aromasin carrying extremely strong natural testosterone stimulating properties, this makes it very appealing for this purpose. Due to the slight androgenic nature and moderately decent promotion of IGF-1 this makes it even more appealing. However, we must consider the primary purpose of Aromasin, which is as an anti-estrogen. High levels of estrogen can be problematic, but the hormone is still necessary to our body’s health. It is important in maintaining a proper immune system, as well as in the maintenance of healthy cholesterol levels. Then consider the PCT, which in part is primarily designed to stimulate natural testosterone production, but the overall primary point is to normalize the body. We cannot normalize with low estrogen levels. For a proper PCT that not only stimulates testosterone production but promotes overall normalization, SERM’s(Clomid and Nolvadex) should always be your first choice.

 

The possible side effects of Aromasin are very similar to the primary AI’s in Arimidex and Letrozole. Many who use the AI often report fatigue and weakness, but this is often not an issue for the anabolic steroid user. The exception would be the steroid user who is in the middle of a harsh cutting cycle, such as in preparation for a bodybuilding contest. Many bodybuilders often report strong lethargy during this period, which isn’t surprising due to the intense diet and often incredible amount of cardio. However, it’s often amplified by the use of an AI like Aromasin. Overall, the primary possible side effects of Aromasin include:

Headaches

Hot Flashes

High Blood Pressure

Joint Pain

Depression (rare)

Nausea and/or Vomiting (rare)

 

In a performance setting, standard Aromasin doses will normally be 12.5-25mg every other day. Most should be fine with 12.5mg every other day, with some getting by with only two to three doses per week. The individual’s total sensitivity and the composition of the steroid in cycle in question will dictate the final outcome. There will be, however, some who require a daily dose with as much as 25mg per day. This should be short lived and only continued as long as necessary due to the possible cholesterol issues. This type of use can prove very useful for the competitive bodybuilder 7-14 days leading up to the completion in an effort to come in as dry and hard as possible. But again, this full dose use is only used for a limited time.

 

The steroid laws of the U.S. are some of the harshest the world over. There are countries that carry laws that are similarly strict but there are numerous that are far more lenient. China and some other countries are heavens for anabolic steroids and other performence-enhancing products. It is imperative you understand the law as it pertains to where you live before you buy any anabolic steroids. Due to the steroid laws of the U.S. and other parts of the world, if you are looking for high quality anabolics or SARMs you are encouraged to visit www.ultrapandaroids.com, which has 3 warehouses located in USA, Hong Kong, and Italy. Ultrapandaroids.com can legally provide you high quality anabolics without a prescription. 

 

Aromasin is an extremely powerful and valuable AI. We cannot necessarily call it more valuable than the more traditional AI’s, but it is useful. In the end, you may have to try varying AI’s at different times to find which one works best for you.

 

If you are using Aromasin during an anabolic steroid cycle, you are strongly encouraged to keep the possible cholesterol issues in mind. Some have suggested that the use of an AI like Aromasin along with a low dose of Nolvadex could protect the individual from cholesterol issues. While there is no concrete data to fully support this, in theory it may work as Nolvadex as an anti-estrogen actively acts as estrogen in the liver, thereby promoting healthier cholesterol levels. Regardless, for your cholesterol health, ensure your diet and lifestyle is cholesterol friendly. A cholesterol friendly lifestyle will be limited in saturated fats and simple sugars. It should also be abundant in omega fatty acids; daily fish oil supplementation is advised. Incorporating plenty of cardiovascular activity into your routine is also advised. Some may also find a cholesterol antioxidant supplement to be useful.

 

 

 

 

It is known that steroidal AIs like Aromasin can bring about hormonal effects besides a lowering of estrogen that we don’t get with Arimidex. 

 

It’s known that Aromasin is able to stimulate the release of luteinizing hormone and follicle stimulating hormone which are both required for testosterone production. But the very dramatic and effective way that Aromasin is able to suppress estrogen can in fact be its downfall for PCT use, where you do need some low level of estrogen as a male in order for testosterone to start normalizing again. Therefore, SERMs like Nolvadex and Clomid are mostly recommended for PCT instead.

 

Some people will combine both that SERM and the AI Aromasin for PCT, and while studies have shown a SERM-AI combination can be counterproductive using other aromatase inhibitor products, this does not seem to be the case with Aromasin. A maximum dosage of 25mg daily for Aromasin during PCT for 2 weeks can be combined with Nolvadex at up to 40mg daily for 4 weeks as an effective PCT cycle – however many men will find that the SERM alone is enough to adequately recover testosterone function and retain your gains.

 

Aromasin is metabolized by the liver and while metabolites are known to be formed during this process, it is still not fully understood how potentially toxic they may be, if at all. There have been rare cases of serious hepatotoxicity from the use of Aromasin in a very small number of women using it long term for cancer treatment but the study states this is a small risk that is outweighed by the benefit of the drug. It is unknown whether liver toxicity is a risk to steroid users making use of Aromasin, but the potential liver toxicity of some anabolic steroids should be of a much greater concern.

 

Fatigue, tiredness or weakness can be reported by women using Aromasin for medical purposes but this is not thought to be a major issue for men using this drug during steroid use unless you’re in the process of a serious cutting phase where your diet is restricted, and it’s possible Aromasin might amplify any fatigue during this time. Taking too high of a dosage or Aromasin can also bring about chronic fatigue and if this does happen, lowering your dose should fix the problem quickly.

 

In a 12 month study focused on women using this drug for breast cancer it was found that Aromasin has a neutral effect on cholesterol, so it did not raise or lower the levels overall. This concerned both total cholesterol, as well as HDL levels (that’s the good cholesterol type). Aromasin also didn’t affect the levels of bad cholesterol (LDL). There was actually a benefit found in this study where Aromasin lowered the levels of triglycerides so less fat lipids are stored in the blood.

 

Despite this study, some other studies have found that Aromasin does in fact lower HDL levels in some women. This tells us that the effects may be highly individual between people, and these results may not necessarily have any bearing on men who use Aromasin over short periods of time while using anabolic steroids.

 

 

Aromatase inhibitors including Aromasin are known to reduce bone mineral density so can lead to a higher risk of bone fractures and more serious diseases like osteoporosis. Exemestane has shown in studies to possibly result in less bone loss than other aromatase inhibitors because of its slightly different androgenic structure.

 

However these studies are on women who are at greater risk of bone loss from lowered estrogen levels that Aromasin causes, There are no studies on men who use this drug to combat steroid side effects as to whether it can pose the same risk for bone loss or osteoporosis.

 

Aromasin is an aromatase inhibitor so it lowers your entire estrogen levels, and gyno is caused by the excess estrogen when you’re using aromatizing steroids like testosterone and derivatives of testosterone like Dianabol. Because Aromasin is so effective at lowering estrogen, possibly as low as 85%, it should work well to prevent or at least greatly minimize the risk of gyno.